“Bacteria and Intracellularity” clearly demonstrates that cellular microbiology as a field has reached maturity, extending beyond the strictly cellular level to infections of various organs and tissues. Decades of intense investigation into host-bacterial pathogen interactions have highlighted common concepts in intracellularity but also very diverse mechanisms underlying the various infections produced by bacteria. This book offers a wide-ranging look at the latest studies, including: • foodborne pathogens, including how, when, and where bacteria interact with the gut and its microbiota • infections of the urogenital tract, endothelial barriers, and the nervous system • major advances in work with Mycobacterium tuberculosis and M. leprae
• subcellular microbiology, including metabolism of infected cells, nuclear biology, and microRNAs • endosymbionts, in particular the latest work with Wolbachia and its effect on insect transmission of viral pathogens • research into cell autonomous defense pathways that has led to major insights into immunology and innate immunity • the latest developments in technology, for the next steps in the study of intracellularity All facets of cellular physiology, within the entire scope of cells and host tissues, can be targeted by pathogens. This book offers to researchers, students, and laboratorians a valuable overview of the state of current research into the cellular microbiology of host-pathogen interactions.
